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Volume 7, Issue 1 (2026)
J Clinic Care Skill 2026, 7(1): 1001-1005 |
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Received: 2025/11/22 | Accepted: 2025/12/6 | Published: 2026/01/11
Received: 2025/11/22 | Accepted: 2025/12/6 | Published: 2026/01/11
How to cite this article
mansourian A, Mohammadhoseini A, Momtahan E. Comparison of the Effects of Propofol and Dexmedetomidine Infusion on Sedation in the Recovery Room in Patients Undergoing Cholecystectomy. J Clinic Care Skill 2026; 7 (1) :1001-1005
URL: http://jccs.yums.ac.ir/article-1-464-en.html
URL: http://jccs.yums.ac.ir/article-1-464-en.html
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1- Associate Professor, Department of Anesthesiology/ Clinical Research Development Unit Shahid Jalil, Yasuj University of Medical Science, Yasuj, Iran.
2- Associate Professor, Department of Anesthesiology/ Clinical Research Development Unit Shahid Jalil, Yasuj University of Medical Science, Yasij, Iran.
3- Student, Department of Anesthesiology/ Clinical Research Development Unit Shahid Jalil, Yasuj University of Medical Science, Yasuj, Iran. ,elhammomtahan2017@gmail.com
2- Associate Professor, Department of Anesthesiology/ Clinical Research Development Unit Shahid Jalil, Yasuj University of Medical Science, Yasij, Iran.
3- Student, Department of Anesthesiology/ Clinical Research Development Unit Shahid Jalil, Yasuj University of Medical Science, Yasuj, Iran. ,
Abstract (60 Views)
Aims: This study aimed to compare the effects of propofol and dexmedetomidine infusion on sedation in the Recovery Room in Patients Undergoing Cholecystectomy.
Methods: This randomized clinical trial was conducted on 71 patients scheduled for laparoscopic cholecystectomy in Yasuj in 2023-2024. Patients were randomly assigned to two groups: 35 received propofol and 36 received dexmedetomidine. The level of agitation was assessed using the Richmond Agitation-Sedation Scale (RASS) at (.) and 40 minutes after surgery by the researcher. Data analysis was performed using SPSS (version 27) software and statistical methods including Chi-square, independent t-test, and paired t-test. A significance level of P < 0.05 was considered.
Findings: The results showed that at 40 minutes after the intervention, the mean agitation level in patients receiving dexmedetomidine [0.22 (0.72)] was lower than that of the propofol group [0.63 (0.81)], indicating better sedation. This difference was statistically significant (p = 0.028).
Conclusion: Dexmedetomidine may be recommended as a preferable option for anesthesia management in patients undergoing laparoscopic cholecystectomy.
Methods: This randomized clinical trial was conducted on 71 patients scheduled for laparoscopic cholecystectomy in Yasuj in 2023-2024. Patients were randomly assigned to two groups: 35 received propofol and 36 received dexmedetomidine. The level of agitation was assessed using the Richmond Agitation-Sedation Scale (RASS) at (.) and 40 minutes after surgery by the researcher. Data analysis was performed using SPSS (version 27) software and statistical methods including Chi-square, independent t-test, and paired t-test. A significance level of P < 0.05 was considered.
Findings: The results showed that at 40 minutes after the intervention, the mean agitation level in patients receiving dexmedetomidine [0.22 (0.72)] was lower than that of the propofol group [0.63 (0.81)], indicating better sedation. This difference was statistically significant (p = 0.028).
Conclusion: Dexmedetomidine may be recommended as a preferable option for anesthesia management in patients undergoing laparoscopic cholecystectomy.
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